Lung Pathology in Septic Shock with Leukopenia

Lung Changes in Shock

In the very beginning stage of the lung changes are Perivascular, capillary wall edema, thickening of the interstitial, lymph and vascular dilatation.  In the late stage of the shock the following changes will occuree  Microthromboses of the lung capillary, polynulcear in­filtration into the interstitial, the existence of polynu­clear in the alveoli, proliferation of interstitial mesenchy­ma,...

[Adrenal insufficiency in children with septic shock].

OBJECTIVE To review the criteria for diagnosing and treating adrenal insufficiency in patients with septic shock. SOURCE OF DATA Articles published in Brazilian and foreign journals selected through these publicationś websites and Medline, as well as references cited in key articles. SUMMARY OF THE FINDINGS The literature reports a range betwen 17 and 54% for the finding of adrenal insuffic...

Septic Shock

Pediatric severe sepsis and septic shock continue to be significant causes of childhood morbidity and mortality worldwide. The following review will highlight some of the controversies surrounding the consensus definitions. It will chronicle recent clinical and translational research, focusing on pediatric sepsis-specific challenges investigators face. It will also address the pathophysiology o...

Septic shock.

Septic shock, the most severe complication of sepsis, is a deadly disease. In recent years, exciting advances have been made in the understanding of its pathophysiology and treatment. Pathogens, via their microbial-associated molecular patterns, trigger sequential intracellular events in immune cells, epithelium, endothelium, and the neuroendocrine system. Proinflammatory mediators that contrib...

Septic Shock in Neonates